Skip to the chart
Intake recordMulti-Disease Diagnosis Framework
Chart no.
HYG-2025-010
Admitted
November 2025
Status
Completed

Subject

HYGIEIA: Multi Disease Diagnosis Framework

AI health platform · 2025

Your health, analyzed intelligently.

Hygieia bundles five independently trained diagnostic models behind one calm interface, writes every result to a tamper-evident chain, and answers questions through Dr. Hygieia, an assistant that reads your own history.

  • 96%+ avg accuracy
  • 5 AI models
  • Blockchain verified
  • Dr. Hygieia assistant
Models
Heart · Diabetes · Skin · Breast ×2
Accuracy
96%+ average, ROC-AUC reported
Records
SHA-256 chained, re-verifiable
Frieren (Frieren: Beyond Journey's End)
Hygieia landing page
User dashboard
User dashboard
Heart risk prediction result
Heart risk prediction result
  • Deep Learning
  • AI
  • TensorFlow
  • Model Training
5Diagnostic models
96%+Average accuracy
253KTraining samples
4Security layers
01The gist

What it does

Hygieia bundles five independently trained diagnostic models behind one interface, so a clinician or a curious patient can move between a heart-risk questionnaire and a dermatology image scan without changing tools.

Every prediction is written to an append-only chain with a SHA-256 hash, which means a result can be re-verified later and any tampering shows up as a broken chain. On top of that sits Dr. Hygieia, a context-aware assistant that can read your own analysis history when it answers.

  • 5 AI models

    Specialised diagnostic and predictive models, each trained and tuned separately.

  • 96%+ accuracy

    Clinical-grade predictions validated with ROC-AUC alongside raw accuracy.

  • Blockchain verified

    Every analysis is hashed and chained, so records can be re-verified later.

  • AI health assistant

    Dr. Hygieia answers with your analysis history in context, not in a vacuum.

  • Dark / light mode

    A calm, accessible interface built for long clinical sessions.

  • Responsive by default

    The same flows work on a ward tablet and on a phone in a waiting room.

02Model portfolio

Five models, one interface

Each model was trained, tuned and scored on its own dataset. Accuracy alone hides class imbalance, so ROC-AUC is reported next to it.

Frieren (Frieren: Beyond Journey's End)
  • Heart Risk

    18 clinical parameters

    99.4%ROC-AUC 99.9%

    Stacking ensemble · 303 samples

  • Diabetes Risk

    Symptom-based analysis

    98.1%ROC-AUC 99.6%

    Random Forest + XGBoost · 520 samples

  • Skin Diagnosis

    AI image analysis

    96.8%ROC-AUC 99.3%

    CNN + Derm Foundation · ISIC + HAM10000

  • Breast Cancer

    10 risk factors

    81.3%ROC-AUC 86.2%

    Voting ensemble · 251,661 samples

  • Breast Tissue

    30 FNA measurements

    97.2%ROC-AUC 99.7%

    Stacking ensemble · 569 samples

ModelAccuracyROC-AUCSamplesArchitecture
Heart Risk99.4%99.9%303Stacking Ensemble
Diabetes Risk98.1%99.6%520Random Forest + XGBoost
Skin Diagnosis96.8%99.3%ISIC + HAM10000CNN + Derm Foundation
Breast Cancer81.3% (flagged: below 90%)86.2% (flagged: below 90%)251,661Voting Ensemble
Breast Tissue97.2%99.7%569Stacking Ensemble
Frieren (Frieren: Beyond Journey's End)
03Under the hood

How a prediction is made

Frieren (Frieren: Beyond Journey's End)

Heart Risk

18 clinical parameters · Stacking Ensemble · 303 samples

  1. Clinical input18 clinical parameters: age, cholesterol, blood pressure and more
  2. Feature engineeringNormalisation, encoding and feature selection
  3. Base learnersRandom Forest + XGBoost + Gradient Boosting
  4. Meta-learnerLogistic regression stacking ensemble
  5. Binary outputHeart disease risk prediction with a confidence score

Input parameters

  • Age
  • Sex
  • Chest pain type
  • Resting BP
  • Cholesterol
  • Fasting blood sugar
  • Resting ECG
  • Max heart rate
  • Exercise angina
  • ST depression
  • ST slope
  • Major vessels
  • Thalassemia
04Interface

Every screen, in context

Captured from the running application with demo data. Use the screens switch to see the light or dark theme.

Frieren (Frieren: Beyond Journey's End)
  1. Guided input

    Context-aware fields with real-time validation and helper text for every medical parameter. Skin lesions are uploaded as images; the other models take questionnaires and lab values.

    • Toggles and units tuned per parameter
    • Image upload with progress states
    • A risk assessment, not a diagnosis, stated on every form
    Heart risk analysis form
    Heart risk analysis form
  2. Result, explained

    Every result shows the risk level, a confidence score, the exact inputs used, the model and method, and its blockchain transaction hash. Dr. Hygieia adds a plain-language reading of what the numbers mean.

    • Risk level and confidence up front
    • Inputs and model details for auditability
    • AI summary generated for the result
    Heart risk prediction result
    Heart risk prediction result
  3. Dr. Hygieia

    A context-aware assistant that answers with your own analysis history in view. Multiple concurrent conversations, streaming responses and direct links into specific results.

    • Streaming answers
    • Session management
    • Deep links to analyses
    Dr. Hygieia chat
    Dr. Hygieia chat
  4. Blockchain verification

    Every record is hashed with SHA-256 and appended to a chain. Verification walks the chain, flags any tampering and gives administrators an oversight dashboard.

    • Immutable audit trail
    • Tamper detection and chain validation
    • Admin oversight and user management
    Blockchain verification dashboard
    Blockchain verification dashboard
05Themes

Calm in daylight, calm at night

Soft surfaces, one green accent, and a dark mode that keeps every card legible. Drag the handle.

Dashboard, light themeDashboard, dark theme
06Responsive

Same flows on a phone

Hover a phone to scroll its screen.

  • Landing
    Landing
  • Dashboard
    Dashboard
  • Heart risk form
    Heart risk form
  • Result
    Result
  • Sign in
    Sign in
07Trust model

Four layers of defence

Authentication

  • JWT token-based auth
  • Bcrypt password hashing
  • Session management

Authorization

  • Role-based access control
  • Admin / user separation
  • Resource ownership validation

Data protection

  • Input validation & sanitisation
  • SQL injection prevention
  • XSS protection

Blockchain

  • SHA-256 cryptographic hashing
  • Immutable audit trail
  • Chain integrity validation

Frontend

  • Next.js 14
  • TypeScript
  • Tailwind CSS
  • Framer Motion
  • TanStack Query
  • Zustand

Backend & models

  • Flask
  • SQLAlchemy
  • JWT
  • scikit-learn
  • TensorFlow
  • Google Derm Foundation
  • Gemini
Frieren (Frieren: Beyond Journey's End)
09Model report

The dermatology model, in depth

Architecture, training, validation and calibration of the skin-lesion classifier.

Frieren (Frieren: Beyond Journey's End)

Want the code, or the next one?